Biosynthesis of 2,5-furan Dicarboxylic Acid by Aspergillus FLavus Apls-1: Process Optimization and Intermediate Product Analysis

Rajesh, R O; Godan, T K; Rai, A K; Sahoo, D; Pandey, A; Binod, P

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dc.contributor.author	Rajesh, R O
dc.contributor.author	Godan, T K
dc.contributor.author	Rai, A K
dc.contributor.author	Sahoo, D
dc.contributor.author	Pandey, A
dc.contributor.author	Binod, P
dc.date.accessioned	2020-02-25T12:03:11Z
dc.date.available	2020-02-25T12:03:11Z
dc.date.issued	2019-03-20
dc.identifier.citation	Bioresource Technology; 284:155-160	en_US
dc.identifier.uri	https://www.sciencedirect.com/science/article/pii/S0960852419304687
dc.identifier.uri	http://10.10.100.66:8080/xmlui/handle/123456789/3486
dc.description.abstract	The aim of the present study was to develop an eco-friendly biological process for the production of 2,5-furan dicarboxylic acid (FDCA) from 5-hydroxy methylfurfuraldehyde (HMF) using microorganisms. Microorganisms were isolated from the soil samples and evaluated for its biotransformation eﬃciency. Among the isolates, Aspergillus ﬂavus APLS-1 was found to be potent for eﬃcient conversion of HMF to FDCA. The bioconversion parameters were optimized by Box-Behnken design. The optimization resulted in 67% conversion eﬃciency where 1g/L HMF (8mM) was transformed to 0.83g/L (6.6mM) FDCA in 14days at pH6.5 with biomass size of 5.7g/L and biomass age 60h. This is the ﬁrst report on Aspergillus sp., capable of detoxifying HMF and produces FDCA.	en_US
dc.language.iso	en	en_US
dc.publisher	Elsevier	en_US
dc.subject	2,5-furan dicarboxylic acid	en_US
dc.subject	Hydroxymethyl furfuraldehyde	en_US
dc.subject	Biotransformation	en_US
dc.subject	Green bioprocess	en_US
dc.subject	Aspergillus ﬂavus	en_US
dc.title	Biosynthesis of 2,5-furan Dicarboxylic Acid by Aspergillus FLavus Apls-1: Process Optimization and Intermediate Product Analysis	en_US
dc.type	Article	en_US