Base-enabled Access to Diastereoselective Spirofuran Oxindoles and γ-functionalized Allenoates

dc.contributor.author	Basavaraja, D
dc.contributor.author	Ajay Krishna, M S
dc.contributor.author	Krishnan, J
dc.contributor.author	Athira, C S
dc.contributor.author	Amrutha, R R
dc.contributor.author	Suresh, E
dc.contributor.author	Sasidhar, B S
dc.date.accessioned	2021-10-27T07:05:27Z
dc.date.available	2021-10-27T07:05:27Z
dc.date.issued	2021
dc.identifier.citation	Chemical Communications; 57(14):1746-1749	en_US
dc.identifier.uri	https://pubs.rsc.org/en/content/articlelanding/2021/cc/d0cc07715a#!divAbstract
dc.identifier.uri	http://hdl.handle.net/123456789/3839
dc.description.abstract	Base assisted divergent reactivity of isatins and allenoates has been achieved, which afforded diastereoselective spirofuran oxindoles and γ-functionalized allenoates. The DBU mediated Morita–Baylis–Hillman (MBH) reaction followed by the cascade annulation through the stabilized β-ammonium enolate intermediate led to the spiro-framework, wherein DABCO furnished the γ-functionalized allenoates. The protocol offers access to biologically relevant functionalized oxindole scaffolds with an excellent substrate scope under mild reaction conditions.	en_US
dc.language.iso	en	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.title	Base-enabled Access to Diastereoselective Spirofuran Oxindoles and γ-functionalized Allenoates	en_US
dc.type	Article	en_US