Tandem Photoisomerization and Transannular Cyclizations of Zerumbone Epoxide: A Model for Diversity-Oriented Synthesis Using Abundant Natural Products

dc.contributor.author	Biji, M
dc.contributor.author	Radhakrishnan, K V
dc.contributor.author	Lankalapalli, R S
dc.date.accessioned	2021-11-18T10:16:58Z
dc.date.available	2021-11-18T10:16:58Z
dc.date.issued	2021-08-06
dc.identifier.citation	Organic Letters; 23(15): 5871-5875.	en_US
dc.identifier.uri	https://pubs.acs.org/doi/10.1021/acs.orglett.1c01997
dc.identifier.uri	http://hdl.handle.net/123456789/3875
dc.description.abstract	Photoirradiation of (6E,9E)-zerumbone-2,3-epoxide afforded a diverse range of transannular cyclized products in the presence of a catalytic amount of Sc(OTf)3. At the behest of the geometrical isomers produced by photoirradiation, the diversity encompasses an unprecedented eudesmane core and oxo-bridged hydroxy-olefin skeletons. Structure elucidation and the stereochemical outcome of the products are described via extensive NMR analysis. The present study serves as a model for tandem photoisomerization and transannular cyclization of natural products with enone/dienone functionality.	en_US
dc.language.iso	en	en_US
dc.publisher	American Chemical Society	en_US
dc.subject	photoisomerization	en_US
dc.subject	cyclization	en_US
dc.subject	ketones	en_US
dc.subject	ethers	en_US
dc.subject	molecular structure	en_US
dc.title	Tandem Photoisomerization and Transannular Cyclizations of Zerumbone Epoxide: A Model for Diversity-Oriented Synthesis Using Abundant Natural Products	en_US
dc.type	Article	en_US