Amphiphilic Fluorescent Probe Self-encored in Plasma to Detect PH Fluctuations in Cancer Cell Membranes

dc.contributor.author	Podder, A
dc.contributor.author	Joseph, MM
dc.contributor.author	Biswas, S
dc.contributor.author	Samanta, S
dc.contributor.author	Maiti, KK
dc.contributor.author	Bhuniya, S
dc.date.accessioned	2021-11-22T09:52:21Z
dc.date.available	2021-11-22T09:52:21Z
dc.date.issued	2021
dc.identifier.citation	Chemical Communications; 57(5): 607-610	en_US
dc.identifier.uri	https://pubs.rsc.org/en/content/articlelanding/2021/cc/d0cc06694j#!divAbstract
dc.identifier.uri	http://hdl.handle.net/123456789/3921
dc.description.abstract	We have developed an amphiphilic pH probe (P1CS) to detect pH levels in the plasma membrane in cancer cells. An elevated fluorescence signal at 550 nm at the cell surface of cancer cells (MDA-MB-231, HeLa cells) prompted the application of P1CS as a pH marker for the cancer cell surface, discriminating it from normal cells (WI-38). Moreover, the probe enables labeling of the surface of multilayered tumor spheroids, which promotes its use as a marker for the surface of tumor tissue.	en_US
dc.language.iso	en	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.subject	pH fluctuations	en_US
dc.subject	cancer cell membrane	en_US
dc.subject	tumor spheroids	en_US
dc.subject	absorption spectroscopy	en_US
dc.title	Amphiphilic Fluorescent Probe Self-encored in Plasma to Detect PH Fluctuations in Cancer Cell Membranes	en_US
dc.type	Article	en_US