A convergent route for the synthesis of BCX-1777 and BCX-4430 from a Boc-protected 2-pyrrolidinone, derived from 2,3,5-tri-O-benzyl-d-ribonolactone, and a dihalogenated pyrrolopyrimidine as the key starting materials is ...

In the present study, we have designed a novel series of pyrazolyl-1,3,4-thiadiazole analogues by accommodating 1,3,4-thiadiazole ring at C – 4 of pyrazole ring with and without an amide linkage; 5-methyl-1,3-diphenyl-N- ...

Among near-infrared (NIR) dyes, squaraine derivatives are applied as efficient sensitizers in optoelectronic and biomedical devices due to their simple synthesis, intense absorption, and emission and exceptional photochemical ...

Data science has been an invaluable part of the COVID-19 pandemic response with multiple applications, ranging from tracking viral evolution to understanding the vaccine effectiveness. Asymptomatic breakthrough infections ...

The use of organically enhanced kaolin clay as reinforcing filler for NR (natural rubber) and blends of NR with NBR (nitrile-butadiene rubber) and poly BR (butadiene rubber) system were investigated on the basis of DMA ...

The post-harvest unit operations of onion umbels are being carried out manually. Tomechanize this process, the present study was carried out to develop an onionumbels thresher. The developed machine works on the principle ...

India is the largest producer of jackfruit (Artocarpus Heterophyllus Lam.) all over theworld. It is an underutilized seasonal fruit rich in vitamins, minerals, proteins, and car-bohydrates. A significant chunk of the ...

Understanding the temperature profile of different packaging materials would be useful for selecting appropriate packaging material for in-bottle pasteurization. The temperature profile of polypropylene, polyethylene (PE), ...

Indiscriminate usage, disposal and recalcitrance of petroleum-based plastics have led to its accumulation leaving a negative impact on the environment. Bioplastics, particularly microbial bioplastics serve as an ...

Diels–Alder photocycloaddition, a well-known textbook reaction, has not been explored in materials chemistry. Herein we describe how this classical photochemistry can be used to modulate the lower critical solution temperature ...