Abstract:
Nutraceuticals have attained substantial attention
due to their health-boosting or disease-prevention characteristics.
Growing awareness about the potential of nutraceuticals
for the prevention and management of diseases affecting
human has led to an increase in the market value of nutraceuticals
in several billion dollars. Nevertheless, limitations
in supply and isolation complications from plants, animals
or fungi, limit the large-scale production of nutraceuticals.
Microbial engineering at metabolic level has been proved as
an environment friendly substitute for the chemical synthesis
of nutraceuticals. Extensively used microbial systems such
as E. coli and S. cerevisiae have been modified as versatile
cell factories for the synthesis of diverse nutraceuticals. This
review describes current interventions in metabolic engineering
for synthesising some of the therapeutically important
nutraceuticals (phenolic compounds, polyunsaturated
