Abstract:
Conversion of glucose to 5-(chloromethyl)furfural (CMF) is one of the wellknown high yield unit processes in lignocellulosic biomass valorization. A
kinetic modeling study was not reported for the reaction, owing to the complexity
in quantification of CMF. Herein we have successfully developed a rapid, sensitive, and specific HPLC method (reverse phase) to quantify the generated CMF
(range: 10–650 μg/mL) in a dichloroethane solvent. The Box–Behnken design of
experiment method employed for the statistical optimization. A kinetic model
was developed based on the homogeneous first-order kinetic model, and the
results are in good agreement with the experiment data. The formation of CMF,
5-(hydroxymethyl)furfural, formic acid, levulinic acid, and humins from glucose
and HCl were modeled using a serial parallel reaction mechanism. The apparent
activation energy (Ea) for glucose decomposition and CMF formation is 99 and
31 kJ/mol.
