Palladium Catalyzed Ring-Opening of Diazabicylic Olefins with 4-Halo-1,3-Dicarbonyl Compounds: Accessing 3(2H)-Furanone-Appended Cyclopentenes

dc.contributor.author	Omanakuttan, V K
dc.contributor.author	Alisha, V
dc.contributor.author	Henning, H
dc.contributor.author	Jubi, J
dc.date.accessioned	2023-05-08T09:41:52Z
dc.date.available	2023-05-08T09:41:52Z
dc.date.issued	2023-02-13
dc.identifier.citation	Organics; 4(1):70-85	en_US
dc.identifier.uri	https://www.mdpi.com/2673-401X/4/1/6
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/4475
dc.description.abstract	We have realized a Pd-catalyzed ring-opening of diazabicyclic olefins with 4-halo-1,3-dicarbonyl compounds. This reaction resulted in the formation of 3(2H)-furanone-appended hydrazino cyclopentenes. The reaction proceeds via the formation of a π-allylpalladium intermediate which is attacked by the active methylene species, and an intramolecular nucleophilic substitution in the 4-halo-1,3-dicarbonyl moiety furnishes the 3(2H)-furanone-substituted cyclopentene. We could extend this methodology to cyclopropane-appended spirotricyclic olefin for synthesizing 3(2H)-furanone-substituted spiro[2.4]hept-5-ene.	en_US
dc.language.iso	en	en_US
dc.publisher	MDPI	en_US
dc.subject	3(2H)-furanone	en_US
dc.subject	diazabicyclic olefins	en_US
dc.subject	4-halo-1,3-dicarbonyl compounds	en_US
dc.title	Palladium Catalyzed Ring-Opening of Diazabicylic Olefins with 4-Halo-1,3-Dicarbonyl Compounds: Accessing 3(2H)-Furanone-Appended Cyclopentenes	en_US
dc.type	Article	en_US