Engineering semi-permeable giant liposomes

dc.contributor.author	Radhakrishnan, S
dc.contributor.author	Nair, K S
dc.contributor.author	Nandi, S
dc.contributor.author	Bajaj, H
dc.date.accessioned	2024-02-26T10:08:37Z
dc.date.available	2024-02-26T10:08:37Z
dc.date.issued	2023-10-31
dc.identifier.citation	Chemical Communications; 59(93):13863-13866	en_US
dc.identifier.uri	https://pubs.rsc.org/en/content/articlelanding/2023/CC/D3CC04039A
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/4725
dc.description.abstract	Giant unilamellar vesicles (GUVs) with a semi-permeable nature are prerequisites for constructing synthetic cells. Here we engineer semi-permeable GUVs by the inclusion of DOTAP lipid in vesicles. Diffusion of molecules of different charge and size across GUVs are reported. Control over size-selective permeability is demonstrated by modulating the DOTAP lipid composition in different lipid systems without reconstituting membrane proteins. Such semi-permeable GUVs have immense applications for constructing synthetic cells.	en_US
dc.language.iso	en	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.title	Engineering semi-permeable giant liposomes	en_US
dc.type	Article	en_US