Radical Cascade Annulation of Biphenyl Acrylamides to Dibenzo‐azepinones: Experimental and DFT Studies

dc.contributor.author	Dupud, R
dc.contributor.author	Thushara, R
dc.contributor.author	Merugu, K K
dc.contributor.author	Suresh, C H
dc.contributor.author	Remya, R
dc.date.accessioned	2025-11-20T08:03:54Z
dc.date.available	2025-11-20T08:03:54Z
dc.date.issued	2024-08-19
dc.identifier.citation	European Journal of Organic Chemistry; 27(31):e202400450	en_US
dc.identifier.uri	https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.202400450
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/5063
dc.description.abstract	An efficient method for the conversion of biphenyl acrylamides to dibenzoazepinones with −SCF3 incorporation is described. This operationally simple radical cascade reaction employs CAN as an oxidant and exhibits good functional group tolerance. Substrates featuring −OCH3, −CH3, −Br or −Cl at the para-position of the aromatic ring exhibits a preference for an ipso-cyclization due to the intervention of DMSO in the reaction. Density functional theory (DFT) calculations provide valuable insights into the reaction's energetics and product selectivity.	en_US
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.title	Radical Cascade Annulation of Biphenyl Acrylamides to Dibenzo‐azepinones: Experimental and DFT Studies	en_US
dc.type	Article	en_US