A Cascade reaction actuated by Nucleophilic heterocyclic carbene catalyzed intramolecular addition of enals via homoenolate to r,β-unsaturated esters: Efficient synthesis of coumarin derivatives.

Abstract

A nucleophilic heterocyclic carbene mediated intramolecular homoenolate reaction strategy for the efficient synthesis of 4-alkyl substituted coumarins is described.